Registering electrophoresis images for bioinformatics study of protein

  • Authors:

  • P. B. Hojte;Xiaoxing Wang

  • Affiliations:

  • Tech. Univ. Denmark, Lyngby, Denmark;Res. Center for Genetic Medicine, Children's Nat. Medical Center, Washington, DC, USA

  • Venue:
  • ICME '03 Proceedings of the 2003 International Conference on Multimedia and Expo - Volume 3 (ICME '03) - Volume 03
  • Year:
  • 2003

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Abstract

Matching 2-D gel electrophoresis images is the first and a major step in bioinformatics study of protein. This paper presents an improved implementation of a thin-plate spline image registration. The effectiveness of the algorithm is demonstrated on matching 2-D gel protein separation profiles.