Analysis and visualization of DNA spectrograms: open possibilities for the genome research

  • Authors:
  • Nevenka Dimitrova;Yee Him Cheung;Michael Zhang

  • Affiliations:
  • Philips Research & Cold Spring Harbor Laboratory;Philips Research & Columbia University;Cold Spring Harbor Laboratory

  • Venue:
  • MULTIMEDIA '06 Proceedings of the 14th annual ACM international conference on Multimedia
  • Year:
  • 2006

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Abstract

The demand for technology that can process biological information is becoming more and more obvious and urgent. Existing research in bioinformatics has been focusing on various types of analysis of DNA sequences and various measurements taken at the protein, RNA transcript and DNA level. In this paper we will show the application of spectral analysis and image processing in analyzing DNA sequences of specific structure. In addition, we extend the framework to visualize long DNA sequences and help in identifying patterns that are visible at high resolution of DNA spectral images.