A multimodel methodology for qualitative model engineering
ACM Transactions on Modeling and Computer Simulation (TOMACS)
Towards the global: complexity, topology and chaos in modelling, simulation and computation
Proceedings from the international conference on complex systems on Unifying themes in complex systems
Multiagent Systems: A Modern Approach to Distributed Artificial Intelligence
Multiagent Systems: A Modern Approach to Distributed Artificial Intelligence
AAMAS '03 Proceedings of the second international joint conference on Autonomous agents and multiagent systems
Cooperative negotiation for soft real-time distributed resource allocation
AAMAS '03 Proceedings of the second international joint conference on Autonomous agents and multiagent systems
A Cooperative Negotiation Protocol for Physiological Model Combination
AAMAS '04 Proceedings of the Third International Joint Conference on Autonomous Agents and Multiagent Systems - Volume 2
On the simulation of multiagent-based regulators for physiological processes
MABS'02 Proceedings of the 3rd international conference on Multi-agent-based simulation II
IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics
Synchronization of decentralized multiple-model systems by market-based optimization
IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics
Anthropic agency: a multiagent system for physiological processes
Artificial Intelligence in Medicine
Diagnostic Knowledge Acquisition for Agent-Based Medical Applications
KES-AMSTA '07 Proceedings of the 1st KES International Symposium on Agent and Multi-Agent Systems: Technologies and Applications
Multi-agent model of hepatitis C virus infection
Artificial Intelligence in Medicine
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Simulating and controlling physiological phenomena are complex tasks to tackle. This is due to the fact that physiological processes are usually described by a set of partial models representing specific aspects of the phenomena and their adoption does not allow the achievement of an effective simulation/control system. A current open issue is the development of techniques able to comprehensively describe a phenomenon exploiting partial models. Simulation and control heavily rely on accurate modelling of physiological systems. In addition, since a large number of partial models of a single physiological phenomenon have been proposed over the years, the evaluation of their effectiveness and of their combinations is a fundamental task. In this paper we propose a multiagent paradigm, called anthropic agency, as a flexible tool to support and evaluate the combination of partial models embedded in agents. We present an agent negotiation paradigm, that improves the one we employed in our previous applications, as a flexible approach to combine optimally the partial models. We formally describe the negotiation protocol and we embed it in a FIPA agent interaction protocol. Furthermore, as an example of practical application, we describe how our paradigm can be a potential solution to the problem of adaptive cardiac pacing. Finally, we experimentally evaluate our approach and we discuss its properties and peculiarities.