Gene subset selection in kernel-induced feature space

  • Authors:
  • Satoshi Niijima;Satoru Kuhara

  • Affiliations:
  • Department of Bioinformatics, Graduate School of Systems Life Sciences, Kyushu University, Hakozaki, Higashi-ku, Fukuoka, Japan;Faculty of Agriculture, Kyushu University, Hakozaki, Higashi-ku, Fukuoka, Japan

  • Venue:
  • Pattern Recognition Letters
  • Year:
  • 2006

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Abstract

This paper proposes a new filter approach to gene subset selection for kernel-based classifiers. We derive kernel forms of several well-known class separability criteria, and gene subset selection based on the kernelized criteria is applied to microarray cancer classification problems. The performance of our proposed strategy is compared in experiments with those of the conventional filter approach as well as gene ranking methods.