Long-term neuronal behavior caused by two synaptic modification mechanisms

  • Authors:
  • Xi Shen;Philippe De Wilde

  • Affiliations:
  • Department of Electrical and Electronic Engineering, Imperial College London, South Kensington Campus, Exhibition Road, London SW7 2BT, UK;Department of Computer Science, Heriot-Watt University, Edinburgh EH14 4AS,UK

  • Venue:
  • Neurocomputing
  • Year:
  • 2007

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Abstract

We report the first results of simulating the coupling of neuronal, astrocyte, and cerebrovascular activity. It is suggested that the dynamics of the system is different from systems that only include neurons. In the neuron-vascular coupling, distribution of synapse strengths affects neuronal behavior and thus balance of the blood flow; oscillations are induced in the neuron-to-astrocyte coupling.