Detailed Exploration of Face-related Processing in Congenital Prosopagnosia: 1. Behavioral Findings
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
Dissociations of Face and Object Recognition in Developmental Prosopagnosia
Journal of Cognitive Neuroscience
Face-selective Activation in a Congenital Prosopagnosic Subject
Journal of Cognitive Neuroscience
Structural Encoding of Human and Schematic Faces: Holistic and Part-Based Processes
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
Journal of Cognitive Neuroscience
Face-specific processing in the human fusiform gyrus
Journal of Cognitive Neuroscience
Electrophysiological studies of face perception in humans
Journal of Cognitive Neuroscience
Differential lateralization for words and faces: Category or psychophysics?
Journal of Cognitive Neuroscience
Fusiform gyrus face selectivity relates to individual differences in facial recognition ability
Journal of Cognitive Neuroscience
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Neuropsychological, event-related potential (ERP), and functional magnetic resonance imaging (fMRI) methods were combined to provide a comprehensive description of performance and neurobiological profiles for K.W., a case of congenital prosopagnosia. We demonstrate that K.W.'s visual perception is characterized by almost unprecedented inability to identify faces, a large bias toward local features, and an extreme deficit in global/configural processing that is not confined to faces. This pattern could be appropriately labeled congenital integrative prosopagnosia, and accounts for some, albeit not all, cases of face recognition impairments without identifiable brain lesions. Absence of face selectivity is evident in both biological markers of face processing, fMRI (the fusiform face area [FFA]), and ERPs (N170). Nevertheless, these two neural signatures probably manifest different perceptual mechanisms. Whereas the N170 is triggered by the occurrence of physiognomic stimuli in the visual field, the deficient face-selective fMRI activation in the caudal brain correlates with the severity of global processing deficits. This correlation suggests that the FFA might be associated with global/configural computation, a crucial part of face identification.