Semantics of Biological Regulatory Networks

  • Authors:
  • Gilles Bernot;Franck Cassez;Jean-Paul Comet;Franck Delaplace;Céline Müller;Olivier Roux

  • Affiliations:
  • LaMI-genopole, UMR CNRS 8042, UEVE, 523 Place des Terrasses, 91025 Evry Cedex, France;IRCCyN, UMR CNRS 6597, BP 92101 1 rue de la Noë, 44321 Nantes Cedex 3, France;LaMI-genopole, UMR CNRS 8042, UEVE, 523 Place des Terrasses, 91025 Evry Cedex, France;LaMI-genopole, UMR CNRS 8042, UEVE, 523 Place des Terrasses, 91025 Evry Cedex, France;LaMI-genopole, UMR CNRS 8042, UEVE, 523 Place des Terrasses, 91025 Evry Cedex, France;IRCCyN, UMR CNRS 6597, BP 92101 1 rue de la Noë, 44321 Nantes Cedex 3, France

  • Venue:
  • Electronic Notes in Theoretical Computer Science (ENTCS)
  • Year:
  • 2007

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Abstract

The aim of the paper is to revisit the model of Biological Regulatory Networks (BRN) which was proposed by Rene Thomas to model the interactions between a set of genes. We give a formal semantics for BRN in terms of transition systems which formalizes the evolution rules given by Rene Thomas. Then we show how to use this model to find interesting properties of a BRN like the set of stable states, cycles etc using tools for analyzing transition systems.