Communicating and mobile systems: the &pgr;-calculus
Communicating and mobile systems: the &pgr;-calculus
Theoretical Computer Science
Information Processing Letters
PI-Calculus: A Theory of Mobile Processes
PI-Calculus: A Theory of Mobile Processes
ESOP'03 Proceedings of the 12th European conference on Programming
Biomolecular Agents as Multi-behavioural Concurrent Objects
Electronic Notes in Theoretical Computer Science (ENTCS)
Modelling coordination in biological systems
ISoLA'04 Proceedings of the First international conference on Leveraging Applications of Formal Methods
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Documentation of knowledge about biological pathways is often informal and vague, making it difficult to efficiently synthesize the work of others into a holistic understanding of a system. Several researchers have proposed solving this problem by modeling pathways using formal languages, which have a precise and consistent semantics. While precise, many of these languages may be too low-level to model feasibly complex pathways. We have developed the Pathway Modeling Language (PML), a high-level language for modeling pathways. PML is based on a biological metaphor of molecules with binding sites and has special constructs for handling compartment changes in pathways. Our preliminary work has shown that PML's language constructs serve as a promising basis for modeling complex pathways in a readable and composable manner.