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This paper describes a new Branch-and-Regret Heuristic for a class of dynamic and stochastic vehicle routing problems. This work is motivated by a real-life problem faced by a major transporter in Norway. The heuristic uses stochastic information during the solution process. The new method is shown to be superior to previous heuristics that are uniquely based on a pure dynamic approach. The proposed heuristic is well suited to problems containing stochastic customers, stochastic demands, or both. © 2007 Wiley Periodicals, Inc. NETWORKS, Vol. 49(4), 330–340 2007