Genome Rearrangements and Sorting by Reversals
SIAM Journal on Computing
Reconstruction of permutations distorted by reversal errors
Discrete Applied Mathematics
Efficient reconstruction of sequences
IEEE Transactions on Information Theory
Reconstruction of permutations distorted by reversal errors
Discrete Applied Mathematics
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The problem of reconstructing permutations on n elements from their erroneous patterns which are distorted by reversal errors is considered in this paper. Reversals are the operations reversing the order of a substring of a permutation. To solve this problem, it is essential to investigate structural and combinatorial properties of a corresponding Cayley graph on the symmetric group Sym"n generated by reversals. It is shown that for any n=3 an arbitrary permutation @p is uniquely reconstructible from four distinct permutations at reversal distance at most one from @p where the reversal distance is defined as the least number of reversals needed to transform one permutation into the other. It is also proved that an arbitrary permutation is reconstructible from three permutations with a probability p"3-1 and from two permutations with a probability p"2~13 as n-~. A reconstruction algorithm is presented. In the case of at most two reversal errors it is shown that at least 32(n-2)(n+1) erroneous patterns are required in order to reconstruct an arbitrary permutation.