Privacy preserving error resilient dna searching through oblivious automata

  • Authors:
  • Juan Ramón Troncoso-Pastoriza;Stefan Katzenbeisser;Mehmet Celik

  • Affiliations:
  • University of Vigo, Vigo, Spain;Philips Research Europe, Eindhoven, Netherlands;Philips Research Europe, Eindhoven, Netherlands

  • Venue:
  • Proceedings of the 14th ACM conference on Computer and communications security
  • Year:
  • 2007

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Abstract

Human Desoxyribo-Nucleic Acid (DNA) sequences offer a wealth of information that reveal, among others, predisposition to various diseases and paternity relations. The breadth and personalized nature of this information highlights the need for privacy-preserving protocols. In this paper, we present a new error-resilient privacy-preserving string searching protocol that is suitable for running private DNA queries. This protocol checks if a short template (e.g., a string that describes a mutation leading to a disease), known to one party, is present inside a DNA sequence owned by another party, accounting for possible errors and without disclosing to each party the other party's input. Each query is formulated as a regular expression over a finite alphabet and implemented as an automaton. As the main technical contribution, we provide a protocol that allows to execute any finite state machine in an oblivious manner, requiring a communication complexity which is linear both in the number of states and the length of the input string.