Harnessing Ontologies for Argument-Based Decision-Making in Breast Cancer

  • Authors:
  • Matt Williams;Anthony Hunter

  • Affiliations:
  • -;-

  • Venue:
  • ICTAI '07 Proceedings of the 19th IEEE International Conference on Tools with Artificial Intelligence - Volume 02
  • Year:
  • 2007

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Abstract

We introduce a novel Ontology-based Argumentation Framework (OAF) that links a logic-based argumentation formalism and description logic ontologies. We show how these two formalisms can be tightly coupled by observing a few simple restrictions, and provides features not available in either formalism alone. Our work is evaluated in a large case study on decision-making in treatment choice in breast cancer, where rules are developed from the results of pub- lished clinical trials, and we present a small subset of this to demonstrate the use of the system. We show that OAF provides five advantages: (1) facilitating the clear use of shared definitions between multiple authors; (2) enabling us to match terms in the ontology and rules with those in the specific domain literature; (3) providing a close fit be- tween structure of clinical trials and the structure of our rules; (4) delivering significant economies in the size of the rule-base compared to existing approaches; (5) allowing us take advantage of developments in both ontological and ar- gumentative approaches. We also demonstrate that even a restricted language such as ours is sufficient to capture enough information to generate arguments that are useful for clinical practice. An early prototype implementation is available.