Accurate anisotropic fast marching for diffusion-based geodesic tractography

  • Authors:
  • S. Jbabdi;P. Bellec;R. Toro;J. Daunizeau;M. Pélégrini-Issac;H. Benali

  • Affiliations:
  • Lab. d'Imagerie Fonctionnelle, INSERM, Paris, France and Fac. de Médecine Pitié Salpêtrière, Univ. Pierre et Marie Curie, Paris, France and Oxford Ctr. for Func. Mag. Res. Img. ...;Lab. d'Imagerie Fonctionnelle, INSERM, Paris and Fac. de Médecine Pitié Salpêtrière, Univ. Pierre et Marie Curie, Paris, France and McConnell Bain Img. Ctr., Montreal Neurol. I ...;Brain & Body Centre, The University of Nottingham, Nottingham, UK;Lab. d'Imagerie Fonctionnelle, INSERM, Paris and Faculté de Médecine Pitié Salpêtrière, Univ. Pierre et Marie Curie, Paris, France and Functional Imag. Lab., Univ. Coll. L ...;Laboratoire d'Imagerie Fonctionnelle, INSERM, Paris, France and Faculté de Médecine Pitié Salpêtrière, Université Pierre et Marie Curie, Paris, France;Lab. d'Imagerie Fonctionnelle, INSERM, Paris and Faculté de Médecine Pitié Salpêtrière, Univ. Pierre et Marie Curie, Paris, France and Unité d'Imagerie Fonctionnelle, ...

  • Venue:
  • Journal of Biomedical Imaging - Recent Advances in Neuroimaging Methodology
  • Year:
  • 2008

Quantified Score

Hi-index 0.00

Visualization

Abstract

Using geodesics for inferring white matter fibre tracts from diffusion-weighted MR data is an attractive method for at least two reasons: (i) the method optimises a global criterion, and hence is less sensitive to local perturbations such as noise or partial volume effects, and (ii) the method is fast, allowing to infer on a large number of connexions in a reasonable computational time. Here, we propose an improved fast marching algorithm to infer on geodesic paths. Specifically, this procedure is designed to achieve accurate front propagation in an anisotropic elliptic medium, such as DTI data. We evaluate the numerical performance of this approach on simulated datasets, as well as its robustness to local perturbation induced by fiber crossing. On real data, we demonstrate the feasibility of extracting geodesics to connect an extended set of brain regions.