New Approaches to Estimation of White Matter Connectivity in Diffusion Tensor MRI: Elliptic PDEs and Geodesics in a Tensor-Warped Space

Authors:
Lauren O'Donnell;Steven Haker;Carl-Fredrik Westin
Affiliations:
-;-;-
Venue:
MICCAI '02 Proceedings of the 5th International Conference on Medical Image Computing and Computer-Assisted Intervention-Part I
Year:
2002

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Abstract

We investigate new approaches to quantifying the white matter connectivity in the brain using Diffusion Tensor Magnetic Resonance Imaging data. Our first approach finds a steady-state concentration/ heat distribution using the three-dimensional tensor field as diffusion/ conductivity tensors. Our second approach casts the problem in a Riemannian framework, deriving from each tensor a local warping of space, and finding geodesic paths in the space. Both approaches use the information from the whole tensor, and can provide numerical measures of connectivity.