Rule-Based Assistance to Brain Tumour Diagnosis Using LR-FIR

  • Authors:
  • Àngela Nebot;Félix Castro;Alfredo Vellido;Margarida Julià-Sapé;Carles Arús

  • Affiliations:
  • Dept. de Llenguatges i Sistemes Informàtics, Universitat Politècnica de Catalunya, Barcelona, Spain 08034;Dept. de Llenguatges i Sistemes Informàtics, Universitat Politècnica de Catalunya, Barcelona, Spain 08034;Dept. de Llenguatges i Sistemes Informàtics, Universitat Politècnica de Catalunya, Barcelona, Spain 08034;Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y, Nanomedicina (CIBER-BBN), Spain and Grup d'Aplicacions Biomèdiques de la RMN (GABRMN) Departament de ...;Grup d'Aplicacions Biomèdiques de la RMN (GABRMN) Departament de Bioquímica i Biología Molecular (BBM). Unitat de Biociències, Universitat Autònoma de Barcelona (UAB), Cer ...

  • Venue:
  • KES '08 Proceedings of the 12th international conference on Knowledge-Based Intelligent Information and Engineering Systems, Part II
  • Year:
  • 2008

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Abstract

This paper describes a process of rule-extraction from a multi-centre brain tumour database consisting of nuclear magnetic resonance spectroscopic signals. The expert diagnosis of human brain tumours can benefit from computer-aided assistance, which has to be readily interpretable by clinicians. Interpretation can be achieved through rule extraction, which is here performed using the LR-FIR algorithm, a method based on fuzzy logic. The experimental results of the classification of three groups of tumours indicate in this study that just three spectral frequencies, out of the 195 from a range pre-selected by experts, are enough to represent, in a simple and intuitive manner, most of the knowledge required to discriminate these groups.