Theory of Modeling and Simulation
Theory of Modeling and Simulation
Combining micro and macro-modeling in DEVS for computational biology
Proceedings of the 39th conference on Winter simulation: 40 years! The best is yet to come
FMSB '08 Proceedings of the 1st international workshop on Formal Methods in Systems Biology
Spatial modeling in cell biology at multiple levels
Proceedings of the Winter Simulation Conference
| Hi-index | 0.00 |
RNA structure is fundamentally important for many biological processes. In the past decades, diverse structure prediction algorithms and tools were developed but due to missing descriptions in clearly defined modelling formalisms it's difficult or even impossible to integrate them into larger system models. We present an RNA secondary structure folding model described in ml-Devs, a variant of the Devsformalism, which enables the hierarchical combination with other model components like RNA binding proteins. An example of transcriptional attenuation will be given where model components of RNA polymerase, the folding RNA molecule, and the translating ribosome play together in a composed dynamic model.