The temporal logic of reactive and concurrent systems
The temporal logic of reactive and concurrent systems
Checking Safe Trajectories of Aircraft Using Hybrid Automata
SAFECOMP '02 Proceedings of the 21st International Conference on Computer Safety, Reliability and Security
LICS '96 Proceedings of the 11th Annual IEEE Symposium on Logic in Computer Science
Object Recognition from Local Scale-Invariant Features
ICCV '99 Proceedings of the International Conference on Computer Vision-Volume 2 - Volume 2
A spatial logic for concurrency (part I)
Information and Computation - TACS 2001
Coordinated Control of Networked Vehicles: An Autonomous Underwater System
Automation and Remote Control
A spatial logic for concurrency--II
Theoretical Computer Science - Special issue: Foundations of wide area network computing
Scalable Modeling and Performance Evaluation of Wireless Sensor Networks
RTAS '06 Proceedings of the 12th IEEE Real-Time and Embedded Technology and Applications Symposium
Learning cycle-linear hybrid automata for excitable cells
HSCC'07 Proceedings of the 10th international conference on Hybrid systems: computation and control
Automated symbolic reachability analysis: with application to delta-notch signaling automata
HSCC'03 Proceedings of the 6th international conference on Hybrid systems: computation and control
Modeling excitable cells using hybrid automata
Modeling excitable cells using hybrid automata
A classification model: syntax and semantics for classification
RSFDGrC'05 Proceedings of the 10th international conference on Rough Sets, Fuzzy Sets, Data Mining, and Granular Computing - Volume Part II
Quadtrees as an Abstract Domain
Electronic Notes in Theoretical Computer Science (ENTCS)
From cardiac cells to genetic regulatory networks
CAV'11 Proceedings of the 23rd international conference on Computer aided verification
A box-based distance between regions for guiding the reachability analysis of spaceex
CAV'12 Proceedings of the 24th international conference on Computer Aided Verification
On temporal logic and signal processing
ATVA'12 Proceedings of the 10th international conference on Automated Technology for Verification and Analysis
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We address the problem of specifying and detecting emergent behavior in networks of cardiac myocytes, spiral electric waves in particular, a precursor to atrial and ventricular fibrillation. To solve this problem we: (1) apply discrete mode abstraction to the cycle-linear hybrid automata (CLHA) we have recently developed for modeling the behavior of myocyte networks; (2) introduce the new concept of spatial superposition of CLHA modes; (3) develop a new spatial logic, based on spatial superposition, for specifying emergent behavior; (4) devise a new method for learning the formulae of this logic from the spatial patterns under investigation; and (5) apply bounded model checking to detect the onset of spiral waves. We have implemented our methodology as the EMERALD tool suite, a component of our EHA framework for specification, simulation, analysis, and control of excitable hybrid automata. We illustrate the effectiveness of our approach by applying EMERALD to the scalar electrical fields produced by our CELLEXCITE simulation environment for excitable-cell networks.