Harmonic Surface Mapping with Laplace-Beltrami Eigenmaps

Authors:
Yonggang Shi;Rongjie Lai;Kyle Kern;Nancy Sicotte;Ivo Dinov;Arthur W. Toga
Affiliations:
Lab of Neuro Imaging, UCLA School of Medicine, Los Angeles, USA;Department of Mathematics, UCLA, Los Angeles, USA;Department of Neurology, UCLA School of Medicine, Los Angeles, USA;Department of Neurology, UCLA School of Medicine, Los Angeles, USA;Lab of Neuro Imaging, UCLA School of Medicine, Los Angeles, USA;Lab of Neuro Imaging, UCLA School of Medicine, Los Angeles, USA
Venue:
MICCAI '08 Proceedings of the 11th International Conference on Medical Image Computing and Computer-Assisted Intervention, Part II
Year:
2008

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Abstract

In this paper we propose a novel approach for the mapping of 3D surfaces. With the Reeb graph of Laplace-Beltrami eigenmaps, our method automatically detects stable landmark features intrinsic to the surface geometry and use them as boundary conditions to compute harmonic maps to the unit sphere. The resulting maps are diffeomorphic, robust to natural pose variations, and establish correspondences for geometric features shared across population. In the experiments, we demonstrate our method on three subcortical structures: the hippocampus, putamen, and caudate nucleus. A group study is also performed to generate a statistically significant map of local volume losses in the hippocampus of patients with secondary progressive multiple sclerosis.