A framework for image-guided breast surgery
Miar'06 Proceedings of the Third international conference on Medical Imaging and Augmented Reality
Deformable templates using large deformation kinematics
IEEE Transactions on Image Processing
Breast image registration by combining finite elements and free-form deformations
IWDM'10 Proceedings of the 10th international conference on Digital Mammography
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3D dynamic contrast enhanced magnetic resonance (MR) images may help to reduce the high re-excision rate associated with breast conserving surgery. However these images are acquired prone, whilst surgery is performed supine which results in a large deformation that limits their usefulness. We describe here a registration technique based on a biomechanical model to account for soft tissue deformation between prone MR imaging and surgery. The accuracies of the individual registration steps are assessed off-line. We then report our first clinical experience with an image-guided surgery system which incorporates these algorithms. The system's accuracy is assessed against tracked ultrasound images, and is determined to be around 5mm for this case.