Querying Protein-Protein Interaction Networks

  • Authors:
  • Guillaume Blin;Florian Sikora;Stéphane Vialette

  • Affiliations:
  • Université Paris-Est, LIGM - UMR CNRS 8049, France;Université Paris-Est, LIGM - UMR CNRS 8049, France;Université Paris-Est, LIGM - UMR CNRS 8049, France

  • Venue:
  • ISBRA '09 Proceedings of the 5th International Symposium on Bioinformatics Research and Applications
  • Year:
  • 2009

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Abstract

Recent techniques increase the amount of our knowledge of interactions between proteins. To filter, interpret and organize this data, many authors have provided tools for querying patterns in the shape of paths or trees in Protein-Protein Interaction networks. In this paper, we propose an exact algorithm for querying graphs pattern based on dynamic programming and color-coding. We provide an implementation which has been validated on real data.