CelOWS: A Service Oriented Architecture to Define, Query and Reuse Biological Models

  • Authors:
  • Ely Edison Matos;Fernanda Campos;Regina Braga;Rodrigo Weber;Daniele Palazzi

  • Affiliations:
  • Master Program in Computational Modeling,;Master Program in Computational Modeling, and Software Quality Research Group,;Master Program in Computational Modeling, and Software Quality Research Group,;Master Program in Computational Modeling, and Computational Physiology Laboratory, Federal University of Juiz de Fora Juiz de Fora, Minas Gerais, Brazil;Master Program in Computational Modeling, and Software Quality Research Group,

  • Venue:
  • ICCS '09 Proceedings of the 9th International Conference on Computational Science: Part I
  • Year:
  • 2009

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Abstract

The amount of information generated by biological research has lead to an intensive use of models. Mathematical and computational modeling needs accurate description to share, reuse and simulate models as formulated by original authors. In this paper, we introduce the Cell Component Ontology - CelO, expressed in OWL-DL. This ontology captures both the structure of a cell model and the properties of functional components. We use this ontology in a Web project --- CelOWS - to describe, query and compose CellML models. It aims to improve reuse and composition of existent components and allow semantic validation of new models.