A New Linear Initialization in SOM for Biomolecular Data

  • Authors:
  • Antonino Fiannaca;Giuseppe Fatta;Alfonso Urso;Riccardo Rizzo;Salvatore Gaglio

  • Affiliations:
  • ICAR-CNR, Consiglio Nazionale delle Ricerche, Palermo, Italy and Dipartimento di Ingegneria Informatica, Universitá di Palermo, Italy;School of Systems Engineering, University of Reading, UK;ICAR-CNR, Consiglio Nazionale delle Ricerche, Palermo, Italy;ICAR-CNR, Consiglio Nazionale delle Ricerche, Palermo, Italy;ICAR-CNR, Consiglio Nazionale delle Ricerche, Palermo, Italy and Dipartimento di Ingegneria Informatica, Universitá di Palermo, Italy

  • Venue:
  • Computational Intelligence Methods for Bioinformatics and Biostatistics
  • Year:
  • 2009

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Abstract

In the past decade, the amount of data in biological field has become larger and larger; Bio-techniques for analysis of biological data have been developed and new tools have been introduced. Several computational methods are based on unsupervised neural network algorithms that are widely used for multiple purposes including clustering and visualization, i.e. the Self Organizing Maps (SOM). Unfortunately, even though this method is unsupervised, the performances in terms of quality of result and learning speed are strongly dependent from the neuron weights initialization. In this paper we present a new initialization technique based on a totally connected undirected graph, that report relations among some intersting features of data input. Result of experimental tests, where the proposed algorithm is compared to the original initialization techniques, shows that our technique assures faster learning and better performance in terms of quantization error.