Use of a domain model to drive an interactive knowledge-editing tool
International Journal of Man-Machine Studies - Knowledge acquisition for knowledge-based systems, part 1. Based on an AAAI work
Design patterns: elements of reusable object-oriented software
Design patterns: elements of reusable object-oriented software
Toward principles for the design of ontologies used for knowledge sharing
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Computers and Biomedical Research
Maintaining and incrementally revalidating a computer-based clinical guideline: a case study
Computers and Biomedical Research
Sharable representation of clinical guidelines in GLIF: relationship to the Arden syntax
Computers and Biomedical Research
GLIF3: a representation format for sharable computer-interpretable clinical practice guidelines
Journal of Biomedical Informatics
Design and implementation of the GLIF3 guideline execution engine
Journal of Biomedical Informatics
Journal of Biomedical Informatics
Epoch: an ontological framework to support clinical trials management
HIKM '06 Proceedings of the international workshop on Healthcare information and knowledge management
Domain-Specific Modeling
Artificial Intelligence in Medicine
Extraction and use of linguistic patterns for modelling medical guidelines
Artificial Intelligence in Medicine
Journal of Biomedical Informatics
Journal of Biomedical Informatics
Bridging the Gap between Informal and Formal Guideline Representations
Proceedings of the 2006 conference on ECAI 2006: 17th European Conference on Artificial Intelligence August 29 -- September 1, 2006, Riva del Garda, Italy
A framework for defining and verifying clinical guidelines: a case study on cancer screening
ISMIS'06 Proceedings of the 16th international conference on Foundations of Intelligent Systems
Verification of temporal scheduling constraints in clinical practice guidelines
Artificial Intelligence in Medicine
Artificial Intelligence in Medicine
A goal-oriented framework for specifying clinical guidelines and handling medical errors
Journal of Biomedical Informatics
Supporting prenatal care in the public healthcare system in a newly industrialized country
Proceedings of the 9th International Conference on Autonomous Agents and Multiagent Systems: Industry track
Identifying treatment activities for modeling computer-interpretable clinical practice guidelines
KR4HC'10 Proceedings of the ECAI 2010 conference on Knowledge representation for health-care
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AIME'11 Proceedings of the 13th conference on Artificial intelligence in medicine
Variation prediction in clinical processes
AIME'11 Proceedings of the 13th conference on Artificial intelligence in medicine
Patterns for collaborative work in health care teams
Artificial Intelligence in Medicine
Using Recommendation to Support Adaptive Clinical Pathways
Journal of Medical Systems
Supporting adaptive clinical treatment processes through recommendations
Computer Methods and Programs in Biomedicine
Summarizing clinical pathways from event logs
Journal of Biomedical Informatics
Methodological Review: Computer-interpretable clinical guidelines: A methodological review
Journal of Biomedical Informatics
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Objective: Transforming narrative guidelines into a computer-interpretable formalism is still a bottleneck in the development of decision-support systems. Our goal was to support this step by providing computer-interpretable templates for representing guideline knowledge using clinical abstractions that are appropriate for particular guideline sub-domains. Methods and materials: We analyzed guidelines taken from the sub-domains of screening and immunization guidelines to find repeatable clinical abstractions and structured them as design templates to support encoding of these guidelines in a computer-interpretable format. To find guidelines for analysis and validation, we (1) searched the National Guideline Clearinghouse for screening guidelines in internal medicine, that have a clinical algorithm, and which were published during 2002-5 and (2) used adult and childhood immunization guidelines developed by Center of Disease Control and Prevention (CDC) and the Institute for Clinical Systems Improvement. Results: We developed two visual templates that structure screening guidelines as algorithms of guideline steps used for screening and data collection and used them to represent the guidelines collected. We validated the computability of the screening templates by executing a screening guideline in a workflow engine. We validated the computability of immunization templates by writing code that, based on represented knowledge, computes immunization due dates and by creating an algorithm that translates the knowledge into computer-interpretable guidelines. Conclusion: We have demonstrated that our templates could be effectively applied to screening and immunization guidelines to produce computer-interpretable representations using domain-level abstractions.