An Integration and Analysis Pipeline for Systems Biology in Crop Plant Metabolism

  • Authors:

  • Stephan Weise;Christian Colmsee;Eva Grafahrend-Belau;Björn Junker;Christian Klukas;Matthias Lange;Uwe Scholz;Falk Schreiber

  • Affiliations:

  • Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany 06466;Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany 06466;Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany 06466;Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany 06466;Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany 06466;Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany 06466;Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany 06466;Leibniz Institute of Plant Genetics and Crop Plant Research (IPK), Gatersleben, Germany 06466

  • Venue:
  • DILS '09 Proceedings of the 6th International Workshop on Data Integration in the Life Sciences
  • Year:
  • 2009

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Abstract

To advance the comprehension of complex biological processes occurring in crop plants (e.g. for improvement of growth or yield) it is of high interest to reconstruct and analyse detailed metabolic models. Therefore, we established a pipeline combining software tools for (1) storage of metabolic pathway data and reconstruction of crop plant metabolic models, (2) simulation and analysis of stoichiometric and kinetic models and (3) visualisation of data generated with these models. The applicability of the approach is demonstrated by a case study of cereal seed metabolism.