Statistical analysis of the Shapley value for microarray games

  • Authors:
  • Stefano Moretti

  • Affiliations:
  • Unit of Molecular Epidemiology, National Cancer Research Institute, Largo R. Benzi 10, 16132 Genoa, Italy

  • Venue:
  • Computers and Operations Research
  • Year:
  • 2010

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Abstract

Game theory may be helpful to analyze the relevance of genes in determining a specific biological condition or response of interest (e.g. a disease of interest) in a population of cells. The first goal of this paper is to understand how accurate is the relevance index provided by the Shapley value on games arising from microarray experiments. Such a question is the prelude to the second subject of this paper, which concerns comparison between the relevance indices under different biological conditions.