CelOWS: An ontology based framework for the provision of semantic web services related to biological models

Authors:
Ely Edison Matos;Fernanda Campos;Regina Braga;Daniele Palazzi
Affiliations:
Master Program in Computational Modeling, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil;Master Program in Computational Modeling, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil and Software Quality Research Group, Federal University of Juiz de Fora, Juiz de Fo ...;Master Program in Computational Modeling, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil and Software Quality Research Group, Federal University of Juiz de Fora, Juiz de Fo ...;Master Program in Computational Modeling, Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil and Software Quality Research Group, Federal University of Juiz de Fora, Juiz de Fo ...
Venue:
Journal of Biomedical Informatics
Year:
2010

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Abstract

The amount of information generated by biological research has lead to an intensive use of models. Mathematical and computational modeling needs accurate description to share, reuse and simulate models as formulated by original authors. In this paper, we introduce the Cell Component Ontology (CelO), expressed in OWL-DL. This ontology captures both the structure of a cell model and the properties of functional components. We use this ontology in a Web project (CelOWS) to describe, query and compose CellML models, using semantic web services. It aims to improve reuse and composition of existent components and allow semantic validation of new models.