Incomplete Lineage Sorting: Consistent Phylogeny Estimation from Multiple Loci

  • Authors:
  • Elchanan Mossel;Sebastien Roch

  • Affiliations:
  • UC Berkeley, Berkeley;Microsoft Research, Redmond

  • Venue:
  • IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
  • Year:
  • 2010

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Abstract

We introduce a simple computationally efficient algorithm for reconstructing phylogenies from multiple gene trees in the presence of incomplete lineage sorting, that is, when the topology of the gene trees may differ from that of the species tree. We show that our technique is statistically consistent under standard stochastic assumptions, that is, it returns the correct tree given sufficiently many unlinked loci. We also show that it can tolerate moderate estimation errors.