Spatio-Temporal Alignment of Sequences
IEEE Transactions on Pattern Analysis and Machine Intelligence
Comparison of Cardiac Motion Across Subjects Using Non-rigid Registration
MICCAI '02 Proceedings of the 5th International Conference on Medical Image Computing and Computer-Assisted Intervention-Part I
Four-Dimensional Processing of Deformable Cardiac PET Data
MMBIA '00 Proceedings of the IEEE Workshop on Mathematical Methods in Biomedical Image Analysis
Construction of a cardiac motion atlas from MR using non-rigid registration
FIMH'03 Proceedings of the 2nd international conference on Functional imaging and modeling of the heart
Fast spatio-temporal free-form registration of cardiac MR image sequences
FIMH'05 Proceedings of the Third international conference on Functional Imaging and Modeling of the Heart
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A 4D registration method for the spatio-temporal alignment of cardiac MR image sequences has been developed. The registration algorithm has the ability not only to correct any spatial misalignment between the image sequences but also any temporal misalignment which maybe the result of differences in the cardiac cycle between subjects and differences in the temporal acquisition parameters. The algorithm uses a 4D transformation model which is separated into a spatial and a temporal component: the spatial component is a 3D affine transformation which corrects for any misalignment between the two image sequences. The temporal component uses an affine transformation which corrects the temporal misalignment caused by differences in the initial acquisition offset and length of the two cardiac cycles. The method was applied to seven cardiac MR image sequences from healthy volunteers. The registration was qualitatively evaluated by visual inspection and quantitatively by measuring the volume difference and overlap of anatomical regions between the sequences. The results indicated a significant improvement in the spatio-temporal alignment of the sequences.