The multiple sequence alignment problem in biology
SIAM Journal on Applied Mathematics
Parallel Multiple Sequences Alignment in SMP Cluster
HPCASIA '05 Proceedings of the Eighth International Conference on High-Performance Computing in Asia-Pacific Region
Journal of Parallel and Distributed Computing
SEPADS'10 Proceedings of the 9th WSEAS international conference on Software engineering, parallel and distributed systems
MT-clustalW: multithreading multiple sequence alignment
IPDPS'06 Proceedings of the 20th international conference on Parallel and distributed processing
Parametrizing multicore architectures for multiple sequence alignment
Proceedings of the 8th ACM International Conference on Computing Frontiers
Load balancing and parallel multiple sequence alignment with tree accumulation
Euro-Par'06 Proceedings of the 12th international conference on Parallel Processing
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This paper presents a parallel version of CLUSTAL W, called pCLUSTAL. In contrast to the commercial SGI parallel Clustal, which requires an expensive shared memory SGI multiprocessor, pCLUSTAL can be run on a range of distributed and shared memory parallel machines, from high-end parallel multiprocessors (e.g. Sunfire 6800, IBM SP2, etc.) to PC clusters, to simple networks of workstations. We have implemented pCLUSTAL using C and the MPI communication library, and tested it on a PC cluster. Our experimental evaluation shows that our pCLUSTAL code achieves similar or better speedup on a distributed memory PC clusters than the commercial SGI parallel Clustal on a shared memory SGI multiprocessor.