Two Methods for Improving Performance of a HMM and their Application for Gene Finding
Proceedings of the 5th International Conference on Intelligent Systems for Molecular Biology
Computational identification of evolutionarily conserved exons
RECOMB '04 Proceedings of the eighth annual international conference on Resaerch in computational molecular biology
Using multiple alignments to improve gene prediction
RECOMB'05 Proceedings of the 9th Annual international conference on Research in Computational Molecular Biology
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The recognition of splicing sites is an important step in gene recognition. We introduce a synthesis method for splicing sites prediction based on short sequence pattern and long sequence pattern. There are some weights in short sequence pattern and long sequence pattern. We regulate weights by simulated anneal. Applying the method to recognize both the true and false splicing sites, the result shows true positive rate and false positive rate and compared with GeneSplicer.