On simulating subjective evaluation using combined objective metrics for validation of 3D tumor segmentation

  • Authors:
  • Xiang Deng;Lei Zhu;Yiyong Sun;Chenyang Xu;Lan Song;Jiuhong Chen;Reto D. Merges;Marie-Pierre Jolly;Michael Suehling;Xiaodong Xu

  • Affiliations:
  • Corporate Technology, Siemens Ltd., China;Corporate Technology, Siemens Ltd., China;Siemens Corporate Research;Siemens Corporate Research;Peking Union Medical College Hospital, China;Medical Solutions, Siemens Ltd., China;Medical Solutions, Siemens Ltd., China;Siemens Corporate Research;Siemens Medical Solutions, Germany;Corporate Technology, Siemens Ltd., China

  • Venue:
  • MICCAI'07 Proceedings of the 10th international conference on Medical image computing and computer-assisted intervention - Volume Part I
  • Year:
  • 2007

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Abstract

In this paper, we present a new segmentation evaluation method that can simulate radiologist's subjective assessment of 3D tumor segmentation in CT images. The method uses a new metric defined as a linear combination of a set of commonly used objective metrics. The weighing parameters of the linear combination are determined by maximizing the rank correlation between radiologist's subjective rating and objective measurements. Experimental results on 93 lesions demonstrate that the new composite metric shows better performance in segmentation evaluation than each individual objective metric. Also, segmentation rating using the composite metric compares well with radiologist's subjective evaluation. Our method has the potential to facilitate the development of new tumor segmentation algorithms and assist large scale segmentation evaluation studies.