Evaluating segmentation error without ground truth

  • Authors:
  • Timo Kohlberger;Vivek Singh;Chris Alvino;Claus Bahlmann;Leo Grady

  • Affiliations:
  • Corporate Research and Technology, Imaging and Computer Vision, Siemens Corp., Princeton, NJ;Corporate Research and Technology, Imaging and Computer Vision, Siemens Corp., Princeton, NJ;American Science and Engineering, Billerica, MA;Corporate Research and Technology, Imaging and Computer Vision, Siemens Corp., Princeton, NJ;HeartFlow, Inc., Redwood City, CA

  • Venue:
  • MICCAI'12 Proceedings of the 15th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part I
  • Year:
  • 2012

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Abstract

The automatic delineation of the boundaries of organs and other anatomical structures is a key component of many medical image processing systems. In this paper we present a generic learning approach based on a novel space of segmentation features, which can be trained to predict the overlap error and Dice coefficient of an arbitrary organ segmentation without knowing the ground truth delineation. We show the regressor to be much stronger a predictor of these error metrics than the responses of Probabilistic Boosting Classifiers trained on the segmentation boundary. The presented approach not only allows us to build reliable confidence measures and fidelity checks, but also to rank several segmentation hypotheses against each other during online usage of the segmentation algorithm in clinical practice.