Using Uncorrelated Discriminant Analysis for Tissue Classification with Gene Expression Data
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
The Journal of Machine Learning Research
Markov blanket-embedded genetic algorithm for gene selection
Pattern Recognition
Classification consistency analysis for bootstrapping gene selection
Neural Computing and Applications
A comparison of generalized linear discriminant analysis algorithms
Pattern Recognition
Gene selection using genetic algorithm and support vectors machines
Soft Computing - A Fusion of Foundations, Methodologies and Applications - Special issue on neural networks for pattern recognition and data mining
A study of cross-validation and bootstrap for accuracy estimation and model selection
IJCAI'95 Proceedings of the 14th international joint conference on Artificial intelligence - Volume 2
A genetic embedded approach for gene selection and classification of microarray data
EvoBIO'07 Proceedings of the 5th European conference on Evolutionary computation, machine learning and data mining in bioinformatics
An effective gene selection method based on relevance analysis and discernibility matrix
PAKDD'07 Proceedings of the 11th Pacific-Asia conference on Advances in knowledge discovery and data mining
A hybrid GA/SVM approach for gene selection and classification of microarray data
EuroGP'06 Proceedings of the 2006 international conference on Applications of Evolutionary Computing
EC'05 Proceedings of the 3rd European conference on Applications of Evolutionary Computing
Informative gene selection and tumor classification by null space LDA for microarray data
ESCAPE'07 Proceedings of the First international conference on Combinatorics, Algorithms, Probabilistic and Experimental Methodologies
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In supervised classification of Microarray data, gene selection aims at identifying a (small) subset of informative genes from the initial data in order to obtain high predictive accuracy. This paper introduces a new embedded approach to this difficult task where a genetic algorithm (GA) is combined with Fisher's linear discriminant analysis (LDA). This LDA-based GA algorithm has the major characteristic that the GA uses not only a LDA classifier in its fitness function, but also LDA's discriminant coefficients in its dedicated crossover and mutation operators. Computational experiments on seven public datasets show that under an unbiased experimental protocol, the proposed algorithm is able to reach high prediction accuracies with a small number of selected genes.