A hybrid GA/SVM approach for gene selection and classification of microarray data

  • Authors:
  • Edmundo Bonilla Huerta;Béatrice Duval;Jin-Kao Hao

  • Affiliations:
  • LERIA, Université d’Angers, Angers, France;LERIA, Université d’Angers, Angers, France;LERIA, Université d’Angers, Angers, France

  • Venue:
  • EuroGP'06 Proceedings of the 2006 international conference on Applications of Evolutionary Computing
  • Year:
  • 2006

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Abstract

We propose a Genetic Algorithm (GA) approach combined with Support Vector Machines (SVM) for the classification of high dimensional Microarray data. This approach is associated to a fuzzy logic based pre-filtering technique. The GA is used to evolve gene subsets whose fitness is evaluated by a SVM classifier. Using archive records of ”good” gene subsets, a frequency based technique is introduced to identify the most informative genes. Our approach is assessed on two well-known cancer datasets and shows competitive results with six existing methods.