Pattern Classification (2nd Edition)
Pattern Classification (2nd Edition)
Discovering Gene Networks with a Neural-Genetic Hybrid
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
Kernel methods for predicting protein--protein interactions
Bioinformatics
Computational Approaches for Predicting Protein---Protein Interactions: A Survey
Journal of Medical Systems
Hierarchical multi-label prediction of gene function
Bioinformatics
Comparative experiments on learning information extractors for proteins and their interactions
Artificial Intelligence in Medicine
IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics
Mining from protein–protein interactions
Wiley Interdisciplinary Reviews: Data Mining and Knowledge Discovery
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A crucial step towards understanding the properties of cellular systems in organisms is to map their network of protein-protein interactions (PPIs) on a proteomic-wide scale completely and as accurately as possible. Uncovering the diverse function of proteins and their interactions within the cell may improve our understanding of disease and provide a basis for the development of novel therapeutic approaches. The development of large-scale high-throughput experiments has resulted in the production of a large volume of data which has aided in the uncovering of PPIs. However, these data are often erroneous and limited in interactome coverage. Therefore, additional experimental and computational methods are required to accelerate the discovery of PPIs. This paper provides a review on the prediction of PPIs addressing key prediction principles and highlighting the common experimental and computational techniques currently employed to infer PPI networks along with relevant studies in the area.