Papsynth: simulated bright-field images of cervical smears

  • Authors:
  • Patrik Malm;Anders Brun;Ewert Bengtsson

  • Affiliations:
  • Centre for Image Analysis, Uppsala, Sweden;Centre for Image Analysis, Uppsala, Sweden;Centre for Image Analysis, Uppsala, Sweden

  • Venue:
  • ISBI'10 Proceedings of the 2010 IEEE international conference on Biomedical imaging: from nano to Macro
  • Year:
  • 2010

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Abstract

In this paper, we present a simulator for bright-field microscope images of "Pap-smears", which is the most common technique used today for cervical cancer screening. Lacking a ground truth for real images, these realistic synthetic images may be used to tune and validate image analysis and processing algorithms. We demonstrate this for two tasks: uncorrelated noise removal and nucleus segmentation. The simulator is a part of a larger project, aiming at automatic, cost efficient screening for cervical cancer in developing countries.