Experimental validation and sensitivity analysis for CFD simulations of cerebral aneurysms

Authors:
Qi Sun;Alexandra Groth;Matthias Bertram;Irina Waechter;Tom Bruijns;Roel Hermans;Vitor Mendes Pereira;Olivier Brina;Til Aach
Affiliations:
Philips Research Europe, Aachen, Germany and Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany;Philips Research Europe, Aachen, Germany;Philips Research Europe, Aachen, Germany;Philips Research Europe, Aachen, Germany;Philips Healthcare, X-ray Pre-Development, Best, The Netherlands;Philips Healthcare, X-ray Pre-Development, Best, The Netherlands;University Hospital of Geneva, Department of Neuroradiology, Geneva, Switzerland;University Hospital of Geneva, Department of Neuroradiology, Geneva, Switzerland;Institute of Imaging and Computer Vision, RWTH Aachen University, Aachen, Germany
Venue:
ISBI'10 Proceedings of the 2010 IEEE international conference on Biomedical imaging: from nano to Macro
Year:
2010

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Abstract

In this work, by exploiting a phantom aneurysm model, we illustrate the correlation between experimental data and computational fluid dynamics (CFD) simulation results under well controlled conditions. This is difficult to achieve with clinical patient cases where several uncertainties are present. Quantitative measures are defined for CFD validation by virtual angiography. In addition, a parametric study has been carried out to systematically investigate the sensitivity of current measuring technique on the flow pattern.