Mitosis extraction in breast-cancer histopathological whole slide images

  • Authors:
  • Vincent Roullier;Olivier Lézoray;Vinh-Thong Ta;Abderrahim Elmoataz

  • Affiliations:
  • Université de Caen Basse-Normandie, ENSICAEN, CNRS, GREYC UMR 6072 - Équipe Image;Université de Caen Basse-Normandie, ENSICAEN, CNRS, GREYC UMR 6072 - Équipe Image;LaBRI, Université de Bordeaux, CNRS, IPB;Université de Caen Basse-Normandie, ENSICAEN, CNRS, GREYC UMR 6072 - Équipe Image

  • Venue:
  • ISVC'10 Proceedings of the 6th international conference on Advances in visual computing - Volume Part I
  • Year:
  • 2010

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Abstract

In this paper, we present a graph-based multi-resolution approach for mitosis extraction in breast cancer histological whole slide images. The proposed segmentation uses a multi-resolution approach which reproduces the slide examination done by a pathologist. Each resolution level is analyzed with a focus of attention resulting from a coarser resolution level analysis. At each resolution level, a spatial refinement by semi-supervised clustering is performed to obtain more accurate segmentation around edges. The proposed segmentation is fully unsupervised by using domain specific knowledge.