Fed-batch cultivation control based on genetic algorithm PID controller tuning

Authors:
Olympia Roeva;Tsonyo Slavov
Affiliations:
Centre of Biomedical Engineering, BAS, Bulgaria;Technical University, Sofia, Bulgaria
Venue:
NMA'10 Proceedings of the 7th international conference on Numerical methods and applications
Year:
2010

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Abstract

In this paper a universal discrete PID controller for the control of E. coli fed-batch cultivation processes is designed. The controller is used to control feed rate and to maintain glucose concentration at the desired set point. Tuning the PID controller, to achieve good closed-loop system performance, using genetic algorithms is proposed. As a result the optimal PID controller settings are obtained. For a short time the controller sets the control variable and maintains it at the desired set point during the process. Application of the designed controller provides maintaining of the accuracy and efficiency of the system performance.