Clinical practice guidelines: A case study of combining OWL-S, OWL, and SWRL
Knowledge-Based Systems
SEMPATH: Semantic Adaptive and Personalized Clinical Pathways
ETELEMED '09 Proceedings of the 2009 International Conference on eHealth, Telemedicine, and Social Medicine
An ontology-based hierarchical semantic modeling approach to clinical pathway workflows
Computers in Biology and Medicine
Towards the Merging of Multiple Clinical Protocols and Guidelines via Ontology-Driven Modeling
AIME '09 Proceedings of the 12th Conference on Artificial Intelligence in Medicine: Artificial Intelligence in Medicine
Knowledge Management for Health Care Procedures
Exploiting OWL reasoning services to execute ontologically-modeled clinical practice guidelines
AIME'11 Proceedings of the 13th conference on Artificial intelligence in medicine
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Handling comorbid diseases in a decision support framework is a challenging problem as it demands the synthesis of clinical procedures for two or more diseases whilst maintaining clinical pragmatics. In this paper we present a knowledge management approach for handling comorbid diseases by the systematic alignment of the Clinical Pathways (CP) of comorbid diseases. Our approach entails: (a) knowledge synthesis to derive disease-specific CP from evidence-bases sources; (b) knowledge modeling to abstract medical and procedural knowledge from the CP; (c) knowledge representation to computerize the CP in terms of a CP ontology; and (d) knowledge alignment by aligning multiple CP to develop a unified CP knowledge model for comorbid diseases. We present the COMET system that provides decision support to handle comorbid cardiac heart failure and atrial fibrillation.