Clinical practice guidelines: A case study of combining OWL-S, OWL, and SWRL
Knowledge-Based Systems
Executing medical guidelines on the web: Towards next generation healthcare
Knowledge-Based Systems
Query Answering for OWL-DL with rules
Web Semantics: Science, Services and Agents on the World Wide Web
Ontology-based knowledge modeling to provide decision support for comorbid diseases
KR4HC'10 Proceedings of the ECAI 2010 conference on Knowledge representation for health-care
Methodological Review: Computer-interpretable clinical guidelines: A methodological review
Journal of Biomedical Informatics
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Ontology-based modeling of Clinical Practice Guidelines (CPG) is a well-established approach to computerize CPG for execution in clinical decision support systems. Many CPG computerization approaches use the Web Ontology Language (OWL) to represent the CPG's knowledge, but they do not exploit its reasoning services to execute the CPG. In this paper, we present our CPG execution approach that leverages OWL reasoning services to execute CPG. In this way, both CPG knowledge representation and execution semantics are maintained within the same formalism. We have developed three different OWL-based CPG execution engines using OWL-DL, OWL 2 and SWRL. We evaluate the efficacy of our execution engines by executing an existing OWL based CPG. We also present a comparison of the execution capabilities of our three CPG execution engines.