Unsupervised Learning of Multiple Motifs in Biopolymers Using Expectation Maximization
Machine Learning - Special issue on applications in molecular biology
FMGA: Finding Motifs by Genetic Algorithm
BIBE '04 Proceedings of the 4th IEEE Symposium on Bioinformatics and Bioengineering
MDGA: motif discovery using a genetic algorithm
GECCO '05 Proceedings of the 7th annual conference on Genetic and evolutionary computation
Comparison of Multiobjective Evolutionary Algorithms: Empirical Results
Evolutionary Computation
Journal of Global Optimization
MOGAMOD: Multi-objective genetic algorithm for motif discovery
Expert Systems with Applications: An International Journal
Bacterial Foraging Optimization Algorithm Integrating Tabu Search for Motif Discovery
BIBM '09 Proceedings of the 2009 IEEE International Conference on Bioinformatics and Biomedicine
Motif Discovery Using Evolutionary Algorithms
SOCPAR '09 Proceedings of the 2009 International Conference of Soft Computing and Pattern Recognition
A fast and elitist multiobjective genetic algorithm: NSGA-II
IEEE Transactions on Evolutionary Computation
IEEE Transactions on Evolutionary Computation
Comparing multiobjective artificial bee colony adaptations for discovering DNA motifs
EvoBIO'12 Proceedings of the 10th European conference on Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics
Comparing multiobjective swarm intelligence metaheuristics for DNA motif discovery
Engineering Applications of Artificial Intelligence
Artificial bee colony algorithm: a survey
International Journal of Advanced Intelligence Paradigms
Journal of Global Optimization
A parallel cooperative team of multiobjective evolutionary algorithms for motif discovery
The Journal of Supercomputing
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In this work we propose the application of a Swarm Intelligence (SI) algorithm to solve the Motif Discovery Problem (MDP), applied to the specific task of discovering novel Transcription Factor Binding Sites (TFBS) in DNA sequences. In the last years there have appeared many new evolutionary algorithms based on the collective intelligence. Finding TFBS is crucial for understanding the gene regulatory relationship but, motifs are weakly conserved, and motif discovery is an NP-hard problem. Therefore, the use of such algorithms can be a good way to obtain quality results. The chosen algorithm is the Artificial Bee Colony (ABC), it is an optimization algorithm based on the intelligent foraging behaviour of honey bee swarm. To solve the MDP we have applied multiobjective optimization and consequently, we have adapted the ABC to multiobjective problems, defining the Multiobjective Artificial Bee Colony (MOABC) algorithm. New results have been obtained, that significantly improve those published in previous researches.