Active shape models—their training and application
Computer Vision and Image Understanding
MICCAI '08 Proceedings of the 11th International Conference on Medical Image Computing and Computer-Assisted Intervention, Part II
Image Guidance for Spinal Facet Injections Using Tracked Ultrasound
MICCAI '09 Proceedings of the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention: Part I
Biomechanically Constrained Groupwise US to CT Registration of the Lumbar Spine
MICCAI '09 Proceedings of the 12th International Conference on Medical Image Computing and Computer-Assisted Intervention: Part I
Registration of a statistical shape model of the lumbar spine to 3D ultrasound images
MICCAI'10 Proceedings of the 13th international conference on Medical image computing and computer-assisted intervention: Part II
IEEE Transactions on Evolutionary Computation
IPCAI'12 Proceedings of the Third international conference on Information Processing in Computer-Assisted Interventions
MICCAI'12 Proceedings of the 15th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part II
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Spinal needle injections for back pain management are frequently carried out in hospitals and radiological clinics. Currently, these procedures are performed under fluoroscopy or CT guidance in specialized interventional radiology facilities. As an alternative, the use of inexpensive ultrasound image guidance promises to reduce the costs and increase the availability and safety of procedure. We propose to eliminate the need for ionizing radiation by creating a statistical shape model of the lumbar vertebrae and registering it to 3D ultrasound volumes of patient using a groupwise registration algorithm. From a total of 35 patient CT volumes, statistical shape models of the L2, L3 and L4 vertebrae are created, including the mean shapes and principal modes of variation. The statistical shape models are simultaneously registered to the 3D ultrasound by interchangeably optimizing the model parameters and their relative poses. We also use a biomechanical model to constrain the relative motion of the individual vertebra models throughout the registration process. The proposed method was validated on three phantoms with realistic spinal curvatures.