Required accuracy of MR-US registration for prostate biopsies

Authors:
Wendy J. M. van de Ven;Geert J. S. Litjens;Jelle O. Barentsz;Thomas Hambrock;Henkjan J. Huisman
Affiliations:
Department of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands;Department of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands;Department of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands;Department of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands;Department of Radiology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Venue:
MICCAI'11 Proceedings of the 2011 international conference on Prostate cancer imaging: image analysis and image-guided interventions
Year:
2011

Citing 2
Cited 1

MR prior based automatic segmentation of the prostate in TRUS images for MR/TRUS data fusion

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Abstract

MR to TRUS guided biopsies can be a cost-effective solution for prostate biopsies. Prostate cancer can be detected on MRI and a biopsy can be directed towards a suspicious region. With the help of an accurate MR-US registration method the tumor can also be targeted under transrectal US guidance. For heterogeneous tumors, the needle should be guided towards the most aggressive part of the tumor. Not the tumor size, but the size of this smaller tumor hotspot determines the required accuracy of the registration. We investigate the percentage of tumors that are heterogeneous and the corresponding hotspot volume. Results show a hotspot in 63% of the tumors, with a median volume of 0.3 cm3. By assuming a spherical shape, the required accuracy can be determined. For a 90% tumor hit-rate, the registration error should be less than 2.87 mm.