AFNI: software for analysis and visualization of functional magnetic resonance neuroimages
Computers and Biomedical Research
Exploring Connectivity of the Brain's White Matter with Dynamic Queries
IEEE Transactions on Visualization and Computer Graphics
Anatomic and electro-physiologic connectivity of the language system: A combined DTI-CCEP study
Computers in Biology and Medicine
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Electrocorticography (ECoG) allows for measurement of task-related local field potentials directly from cortex in neurosurgical patients. Diffusion tensor imaging (DTI) tractography is an MRI technique that allows for reconstruction of brain white matter tracts, which can be used to infer structural connectivity. This paper reports a novel merger of these two modalities. A processing stream is described in which fiber tracts near intracranial macroelectrodes showing task-related functional responses are isolated to explore structural networks related to working memory maintenance. Results show that ECoG-constrained tractography is useful for revealing structural connectivity patterns related to spatially- and temporally-specific functional responses.