Anatomic and electro-physiologic connectivity of the language system: A combined DTI-CCEP study

  • Authors:

  • Christopher R. Conner;Timothy M. Ellmore;Michael A. DiSano;Thomas A. Pieters;Andrew W. Potter;Nitin Tandon

  • Affiliations:

  • Vivian L. Smith Department of Neurosurgery, University of Texas Medical School at Houston, USA;Vivian L. Smith Department of Neurosurgery, University of Texas Medical School at Houston, USA;Vivian L. Smith Department of Neurosurgery, University of Texas Medical School at Houston, USA;Vivian L. Smith Department of Neurosurgery, University of Texas Medical School at Houston, USA;Vivian L. Smith Department of Neurosurgery, University of Texas Medical School at Houston, USA;Vivian L. Smith Department of Neurosurgery, University of Texas Medical School at Houston, USA

  • Venue:
  • Computers in Biology and Medicine
  • Year:
  • 2011

Quantified Score

Hi-index 0.00

Visualization

Abstract

Here we present a novel multimodal analysis of network connectivity in the language system. We assessed connectivity of Broca's area using tractography with diffusion tensor imaging (DTI), and with cortico-cortical evoked potentials (CCEPs) to measure the spread of artificial currents applied directly to human cortex. We found that both the amplitude and latency of CCEP currents significantly correlates (r^2=0.41, p