MinePhos: A Literature Mining System for Protein Phoshphorylation Information Extraction

Authors:
Yun Xu;Da Teng;Yiming Lei
Affiliations:
University of Science and Technology of China, Hefei and Anhui Province Key Laboratory of High Performance Computing, Hefei;University of Science and Technology of China, Hefei and Anhui Province Key Laboratory of High Performance Computing, Hefei;University of Science and Technology of China, Hefei and Anhui Province Key Laboratory of High Performance Computing, Hefei
Venue:
IEEE/ACM Transactions on Computational Biology and Bioinformatics (TCBB)
Year:
2012

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Abstract

The rapid growth of scientific literature calls for automatic and efficient ways to facilitate extracting experimental data on protein phosphorylation. Such information is of great value for biologists in studying cellular processes and diseases such as cancer and diabetes. Existing approaches like RLIMS-P are mainly rule based. The performance lays much reliance on the completeness of rules. We propose an SVM-based system known as MinePhos which outperforms RLIMS-P in both precision and recall of information extraction when tested on a set of articles randomly chosen from PubMed.