DNA Computing in Microreactors
DNA 7 Revised Papers from the 7th International Workshop on DNA-Based Computers: DNA Computing
Flows in micro fluidic networks: From theory to experiment
Natural Computing: an international journal
Building the components for a biomolecular computer
DNA'04 Proceedings of the 10th international conference on DNA computing
Abstraction layers for scalable microfluidic biocomputing
Natural Computing: an international journal
Emerging Models of Computation: Directions in Molecular Computing
Software-Intensive Systems and New Computing Paradigms
A proposed modularized DNA computer, based on biochips
Proceedings of the first ACM/SIGEVO Summit on Genetic and Evolutionary Computation
Abstraction layers for scalable microfluidic biocomputers
DNA'06 Proceedings of the 12th international conference on DNA Computing
| Hi-index | 0.00 |
We propose a way of implementing a biomolecular computer in the laboratory using deoxyribozyme logic gates inside a microfluidic reaction chamber. We build upon our previous work, which simulated the operation of a flip-flop and an oscillator based on deoxyribozymes in a continuous stirred-tank reactor (CSTR). Unfortunately, using these logic gates in a laboratory-size CSTR is prohibitively expensive, because the reagent quantities needed are too large. This motivated our decision to design a microfluidic system. We would like to use a rotary mixer, so we examine how it operates, show how we have simulated its operation, and discuss how it affects the kinetics of the system. We then show the result of simulating both a flip-flop and an oscillator inside our rotary mixing chamber, and discuss the differences in results from the CSTR setting.