Harmonic skeleton guided evaluation of stenoses in human coronary arteries

Authors:
Yan Yang;Lei Zhu;Steven Haker;Allen R. Tannenbaum;Don P. Giddens
Affiliations:
Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA;Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA;Surgical Planning Lab, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA;Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA;Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA
Venue:
MICCAI'05 Proceedings of the 8th international conference on Medical Image Computing and Computer-Assisted Intervention - Volume Part I
Year:
2005

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Abstract

This paper presents a novel approach that three-dimensionally visualizes and evaluates stenoses in human coronary arteries by using harmonic skeletons. A harmonic skeleton is the center line of a multi-branched tubular surface extracted based on a harmonic function, which is the solution of the Laplace equation. This skeletonization method guarantees smoothness and connectivity and provides a fast and straightforward way to calculate local cross-sectional areas of the arteries, and thus provides the possibility to localize and evaluate coronary artery stenosis, which is a commonly seen pathology in coronary artery disease.