Hypothesis testing with nonlinear shape models

  • Authors:
  • Timothy B. Terriberry;Sarang C. Joshi;Guido Gerig

  • Affiliations:
  • Dept. of Computer Science;Dept. of Computer Science;Dept. of Computer Science

  • Venue:
  • IPMI'05 Proceedings of the 19th international conference on Information Processing in Medical Imaging
  • Year:
  • 2005

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Abstract

We present a method for two-sample hypothesis testing for statistical shape analysis using nonlinear shape models. Our approach uses a true multivariate permutation test that is invariant to the scale of different model parameters and that explicitly accounts for the dependencies between variables. We apply our method to m-rep models of the lateral ventricles to examine the amount of shape variability in twins with different degrees of genetic similarity.